
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 160 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at $30 per night before taxes and fees

Verified guest reviews
Over 14,330 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Vacation rentals with a pool
50 properties feature pools

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
160 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Golfland Sunsplash, Sloan Park, and Hohokam Stadium
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Cozy Casita with kitchenette
Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.
LocationFamilyCleanliness

Urban Cabin - A unique Retreat
Escape to this one-of-a-kind cedar cabin, offering a private sanctuary in the heart of the city. Thoughtfully designed w/a modern edge, it features expansive windows flooding interior w/natural light yet maintaining a cozy, secluded feel. Outside, a private yard, where you'll find an antique clawfoot tub/shower, perfect for unwinding under the open sky. Inside, industrial elements blend seamlessly w/warm cedar tones, creating an inviting atmosphere ideal for both relaxation & inspiration.
LocationValueAir conditioning

Historic Firehouse Downtown Chandler Large shower
Welcome to the historic Firehouse, where you're a quick 5-minute stroll away from bustling Downtown Chandlers top-notch restaurants and bars. You're staying in a historic building that has been magically transformed into a cozy Airbnb retreat. Step Inside the Firehouse Garden with 2 stylish bedrooms that are ready to whisk you away into dreamland, 1 amazing bathroom. With enough space to accommodate up to 6 guests. This is the perfect spot for a getaway with your favorite people.
FamilyLocationAmenities

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.
LocationFamilyWalkability

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).
FamilyValueKitchen

Detached Guesthouse | Full Kitchen & Parking
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!
FamilyLocationBackyard

Cottage
Have you ever wanted to try a tiny house? The Casita is your chance! The Casita is a sparkling clean, small studio that has everything you need for your stay! The Casita is nicely located to Route 60 2miles. then to 101, 202 and I10. Mesa Convention center, Mesa Arts Center and Mesa Amphitheatre: 2 miles. ASU 8 miles. MCC 2 miles. Phoenix 19 miles. and Scottsdale 13 mi. Also many casinos, golf courses and hiking trails. Come enjoy the East Valley!
ValueFamilyQuiet

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.
ValueLocationPets

Private-Detached Guesthouse & Zen Courtyard
Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.
FamilyLocationAir conditioning

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.
LocationFamilyCheck-in

Adorable 1-bedroom guest house with hot tub
Kick back in this calm and stylish space. Close to some of the best hiking trails in the valley. Beautiful Mountain View’s from the hot tub. Great sunsets in a Sonoran desert natural setting. Kitchenette with fridge and microwave, as well as filtered water and coffee. Easy access to all the Phoenix suburbs from the 202 freeway.
ValueLocationHospitality

The White Barn @ Freedom Farms
Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.
LocationFamilyComfort
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Poolside Casita | Goats & Alpacas | Urban Farm
FamilyValueSolo travel

The Oasis Hideout
LocationFamilyLayout

Two Bedroom, Clean Guest House in Gilbert
ValueLocationShared spaces

Cozy casita in a beautiful setting
FamilyLocationPool

The Mesa Cottage
FamilyLocationWalkability

Private studio! Central to popular locations.
ValueLocationTV

Entire Suite: Private and Cozy Clark House Casita
FamilyValueKitchen

Private Luxury Guesthouse in Mesa
ValueLocationSolo travel
Guest house rentals with a patio

Backyard Bungalow | Pool | Near Airport
FamilyValueBathroom

Granada - Adorable, Chic Studio Apt Biltmore Area
ValueFamilyKitchen

Ruby's Hideaway, a historic red brick studio.
LocationValueCondition

Private yard - Short walk to Mill - Historic House
ValueLocationSleep quality

Charming & spacious Casita! Like home only better!
LocationFamilyLayout

Modern Charming Studio: Prime Location & Top Value
LocationFamilyIndoor spaces

Beautiful little house
LocationFamilySleep quality

Paradise Valley Luxe Casita + Private Oasis
FamilyValueHot tub
Guest house rentals with a washer and dryer

Centrally Located Renovated Guest House
FamilyValueKitchen

Downtown Phx | Private Guesthouse & Parking
ValueLocationCleanliness

Enchanting Ahwatukee Secret Casita
LocationValueComfort

South Mountain Hideaway
LocationFamilyNearby

Spacious Studio in Uptown Historic Neighborhood
FamilyLocationOutdoor spaces

Guest suite in downtown Tempe
FamilyValueComfort

Unique urban habitat near ASU/downtown Tempe
FamilyLocationGetting around

Quiet 2BR Guesthouse on Acre -Gym/Newly built
FamilyLocationHiking
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- Phoenix Convention Center
- Lake Pleasant
- Chase Field
- Grand Canyon University
- State Farm Stadium
- TPC Scottsdale - Champions Course
- Grayhawk Golf Club
- The Westin Kierland Golf Club
- Peoria Sports Complex
- Desert Diamond Arena
- Salt River Fields at Talking Stick
- Arizona State University
- Surprise Stadium
- Footprint Center
- WestWorld of Scottsdale
- Sloan Park
- Tempe Beach Park
- Goodyear Ballpark
- Westgate Entertainment District
- Scottsdale Stadium
- Salt River Tubing
- Papago Park
- Camelback Ranch
- We-Ko-Pa Golf Club
- Things to do Mesa
- Things to do Maricopa County
- Food and drink Maricopa County
- Sports activities Maricopa County
- Nature and outdoors Maricopa County
- Things to do Arizona
- Entertainment Arizona
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- Art and culture Arizona
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- Wellness Arizona
- Sightseeing Arizona
- Things to do United States
- Food and drink United States
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- Nature and outdoors United States
- Family travel hub Tips and inspiration
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- Outdoor adventure Explore nature with the family
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- Kid-friendly state parks Check out these family-friendly hikes







