
Family-friendly vacation rentals in Seneca
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Seneca

Total vacation rentals
Explore 50 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at $80 per night before taxes and fees

Verified guest reviews
Over 1,560 verified reviews to help you choose

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
50 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated family-friendly rentals in Seneca
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.
FamilyKitchenAccuracy

Farm Geodome Near Lake Jocassee, Hot Tub, Zip Line
Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.
KitchenIndoor spacesWifi

The Wildflower
Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.
Indoor spacesKitchenLocation

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.
KitchenIndoor spacesRiver

The Cozy Cottage
Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!
FamilyKitchenSleep quality

Holliday's Inn Tiny Tree-house
Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!
KitchenFamilyBackyard

5 Min to Clemson | Hot Tub | Game Room | 5 Kings
5 minutes to Clemson University & Lake Keowee with a private saltwater hot tub, full arcade-style game room and stocked bar—perfect for families or game-day groups! 4 spacious bedrooms, 7 total beds High-speed Wi-Fi & smart TVs in every room Outdoor deck with grill, fire-pit & cornhole Fully equipped kitchen + coffee bar Rated 4.9★ by 171 guests and hosted by a local husband/wife team who lives nearby for quick help. Book your Clemson retreat today—dates fill fast!
FamilyIndoor spacesHiking

Singing Pines Cottage
Right among the pines of South Carolina you will find our cottage. It's 5 minutes from the Historic Ram Cat Alley with Live Outdoor music every Thursday Night (Apr.-Oct.), Shopping, Boutiques, Restaurants, Breweries, and Coffee Shops. It's only 12 minutes from Clemson University, and a short drive to Lake Keowee, Lake Jocassee, and Lake Hartwell. This area is home to numerous Waterfalls, Hiking Trails, and good southern barbecue. We do not host work crews.
KitchenFamilyComfort

Oak Hill Getaway
Right between Seneca and Clemson you will find our getaway. It's 5 mins from Historic Ram Cat Alley with shopping, restaurants, and breweries with Jazz on the Alley music every Thursday night (April - Oct.) It's only 10 minutes from Clemson University. Surrounded by 3 different lakes Jocassee, Keowee, and Hartwell with just a short drive away. You can ride 30 mins up to the mountains where you can hike trails and see waterfalls the foothills have to offer.
KitchenFamilyPets

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.
KitchenIndoor spacesDecor

Tiny house
BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.
FamilyKitchenQuiet

5 Min to Clemson | Large Driveway & Self Check-In
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.
KitchenFamilyCleanliness
Popular amenities for Seneca family-friendly rentals
Family-friendly home rentals with a hot tub

Lake Keowee Cabin: Peaceful and Bright
KitchenIndoor spacesSleep quality

Shady Rest
FamilyKitchenTV

Hidden Lake Sanctuary
Indoor spacesKitchenCheck-in

Lakefront dock *hot tub* Anderson/Clemson king bed
Indoor spacesKitchenBathroom

YOUR OWN Waterfall+Hot Tub+Fire Pit+Sauna
KitchenIndoor spacesLaundry

A-Frame Lake Hartwell Cottage w/ Hot Tub
KitchenFamilySleep quality

Lake Keowee, Waterfront Cabin, 2-Story Dock!
KitchenFamilyComfort

Lakeside Retreat • Pet friendly • Fire Pit
FamilyKitchenQuiet
Family- and pet-friendly home rentals

Getaway on Lake Hartwell: Pontoon Rental, Clemson
FamilyKitchenView

Lake Hartwell house w/ dock 2 miles from Clemson.
FamilyKitchenQuiet

Adjacent to Dawson Park/1 mile from Clemson Univ
Indoor spacesKitchenLayout

Clemson Mom Apartment
FamilyIndoor spacesNearby

Hartwell Escape 6 mi to Clemson Beautiful views
FamilyIndoor spacesLocation

Lit'l Bit O' Heaven- Rocky Top Lodge
KitchenIndoor spacesPets

Beautiful Lake Keowee Condo with great Amenities
Indoor spacesKitchenValue

Renfrow's Retreat
KitchenFamilyGetting around
Family-friendly home rentals with a pool

Clemson Cedarwood Condo with a Deck
KitchenFamilyComfort

Quiet 3-bedroom Cottage at Lake Hartwell
KitchenIndoor spacesDecor

Lisa’s Lodge
Indoor spacesFamilyView

Lakefront 2BR+/2BA w/ a Dock On Lake Hartwell
KitchenIndoor spacesHiking

Lake house w/ a pool and Pickleball court
KitchenFamilyNearby

Perfect Tigertown Condo
FamilyIndoor spacesWifi

Mt Laurel-Walk to Main Street!
FamilyKitchenAmenities

Lovely 2-bedroom apartment in welcoming Seneca
Indoor spacesFamilyCheckout
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