
Apartment vacation rentals in Panama
Find and book unique apartments on Airbnb
Top-rated apartment rentals in Panama
Guests agree: these apartments are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
LocationFamilyHospitality

Best Location – Fancy Apartment in Casco Viejo
Experience absolute luxury in our fully remodeled loft, with access to a spectacular 360° rooftop terrace, where you'll enjoy breathtaking views of the city and skyline. The building also features an elevator for your convenience. Located right in front of a vibrant plaza with renowned restaurants, the location is truly unbeatable, and security in the area is excellent. Relax in the rooftop, enjoy sunset views from the terrace, and experience the unique charm of Panama’s historic Casco Antiguo
ValueLocationHospitality

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!
ValueLocationWalkability

Casa Melina Torio Cozy upscale 2b jungle apartment
Stylish jungle two bedroom apartment Walking distance 5 restaurants. attractions: waterfall, jungle trails, River, Beach & Morrillo Surf break. Fully equipped with everything you need & want (Drinking water filter, Hot water, AC, Starlink WiFi & TV). Perfect for a couple/family seeking to blend work and play. Designed so our guests can fully experience our Torio culture. Cook with local fresh ingredients, discover Torio on foot & return to rest in the coziest rental you have ever experienced.
ValueLocationOutdoor spaces

Luxury Mid-Century Apartment In Casco Viejo
Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.
ValueFamilyAmenities

Pebos Reef Apt 1 · Beachfront · Sea View Terrace
This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.
LocationFamilyGrill

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
FamilyValueSleep quality

Colonial style with calicanto and private balcony
Welcome to a cozy apartment where the charm of the calicanto walls blends with warm details and a perfect balcony to enjoy the atmosphere and the view of the Old Town. We have a prime location on one of the main avenues of the Casco. From here you can easily access historic sites, restaurants, cafes, bars and charming spots. The idea is for you to arrive, feel comfortable, and enjoy the city at your own pace, whether alone, as a couple, or as a family.
FamilyValueCheck-in

Impressive ocean and Panama City views
Enjoy a unique experience, a modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your home. Unbeatable Location Located just 5 minutes from the charming Casco Viejo and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building
LocationValueAccess

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location
ValueLocationIndoor spaces

Moderno, céntrico y cómodo (104)
Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)
LocationFamilyBeach

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
LocationValueComfort
Popular amenities for Panama apartment rentals
Weekly apartment rentals

Walk to Everything | Luxury Stay in Casco Viej
LocationValueAccess

Gorgeous Flat in the best location in Casco Viejo
FamilyLocationOutdoor spaces

Most Beautiful Loft in the Heart of Casco Viejo
LocationValueWalkability

Villas La Fontana Spacious ApartaSuite - Pool 104
ValueFamilyAir conditioning

Luxury Centric 2BR Apartment in Casco Viejo
FamilyValueCondition

Panoramic Ocean View | The Sands
LocationHospitalityView

Casa Esmeralda Refined 120 m² Duplex in Casco Viejo
ValueFamilyBathroom

Amazing experience in Casco Viejo historical site3
LocationQuietSleep quality
Private apartment rentals

Luxury Apartment | Walk to Restaurants & Shops
LocationWalkabilityHospitality

A warm and cozy flat in Casco Viejo
LocationCleanlinessAccess

Escape to the Pacific of Panama
FamilyLocationHospitality

3-bedroom apartment with exceptional waterfront views
LocationAmenitiesSleep quality

Suite Luxury 30th View , Cinta Costera Panama
LocationValueParking

Tropicool Casco Loft w/King Bed & Rooftop
LocationValueHospitality

Seaview Studio
DecorPoolHospitality

Casa de Mono | Tropical Garden Retreat, Near Ocean
ValueFamilyAir conditioning
Apartment rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts
LocationValueWalkability

New Flat with Ocean + City Views
LocationValueLong stay

Spacious 4Br Beachside Getaway at Playa Escondida
LocationValueView

Beachfront Paradise in a 5-star resort
LocationFamilyCondition

Tropical Paradise at Playa Bonita
ValueLocationCheck-in

Marina House at Playa Escondida Resort
FamilyLocationLaundry

Ocean View Apartment - Playa Escondida Resort
LocationFamilyCondition

Apartment #4 Greenscape Suite
ValueFamilyBathroom
Destinations to explore
- Lakehouse rentals Panama
- Pet-friendly rentals Panama
- Beach condo rentals Panama
- Rentals with breakfast Panama
- Rentals with an accessible height bed Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with a sauna Panama
- Nature eco lodge rentals Panama
- Rentals with beach access Panama
- Chalet rentals Panama
- Loft rentals Panama
- Bungalow rentals Panama
- Bed and breakfasts Panama
- Boutique hotels Panama
- Shipping container rentals Panama
- Tent rentals Panama
- Cottage rentals Panama
- Townhouse rentals Panama
- Cabin rentals Panama
- Hostel rentals Panama
- Vacation home rentals Panama
- Family-friendly rentals Panama
- Treehouse rentals Panama
- Dome rentals Panama
- Condo rentals Panama
- Rentals with lake access Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- House rentals Panama
- Rentals with a hot tub Panama
- Farmstay rentals Panama
- Beach house rentals Panama
- Guesthouse rentals Panama
- Island rentals Panama
- Villa rentals Panama
- Waterfront rentals Panama
- Boat rentals Panama
- Tiny house rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with pools Panama
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes





